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LoQ of the INNOVANCE Antithrombin assay on different analyzers. ∗Data taken from 510(k) submission K250965 . AT, antithrombin; AT-DR, antithrombin-based dose regimen; LoQ, limit of quantification.

Journal: Research and Practice in Thrombosis and Haemostasis

Article Title: Analytical validity of the INNOVANCE Antithrombin assay for the measurement of antithrombin activity at fitusiran clinical decision points

doi: 10.1016/j.rpth.2026.103450

Figure Lengend Snippet: LoQ of the INNOVANCE Antithrombin assay on different analyzers. ∗Data taken from 510(k) submission K250965 . AT, antithrombin; AT-DR, antithrombin-based dose regimen; LoQ, limit of quantification.

Article Snippet: To test AT activity in patient plasma throughout the fitusiran clinical development program (phase 1, 2, and 3 clinical trials, excluding China), the INNOVANCE Antithrombin assay was used with the BCS XP analyzer, both from Siemens Healthineers.

Techniques: